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Links between accelerated replicative cellular senescence and down-regulation of SPHK1 transcription

We have identified a mechanism to diminish the proliferative capacity of cells during cell expansion using human adipose-derived stromal cells (hAD-SCs) as a model of replicative senescence. hAD-SCs of high-passage numbers exhibited a reduced proliferative capacity with accelerated cellular senescen...

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Detalles Bibliográficos
Autores principales:	Kim, Min Kyung, Lee, Wooseong, Yoon, Gang-Ho, Chang, Eun-Ju, Choi, Sun-Cheol, Kim, Seong Who
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476483/ https://www.ncbi.nlm.nih.gov/pubmed/30885289 http://dx.doi.org/10.5483/BMBRep.2019.52.3.012

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