Downregulation of FoxM1 sensitizes nasopharyngeal carcinoma cells to cisplatin via inhibition of MRN-ATM-mediated DNA repair

Chemoresistance is the primary obstacle in the treatment of locally advanced and metastatic nasopharyngeal carcinoma (NPC). Recent evidence suggests that the transcription factor forkhead box M1 (FoxM1) is involved in chemoresistance. Our group previously confirmed that FoxM1 is overexpressed in NPC...

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Detalles Bibliográficos
Autores principales: Li, Dandan, Ye, Lin, Lei, Yue, Wan, Jie, Chen, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476488/
https://www.ncbi.nlm.nih.gov/pubmed/30638177
http://dx.doi.org/10.5483/BMBRep.2019.52.3.249

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