Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis

Candida parapsilosis (C. parapsilosis) has become a common pathogen, especially in immunocompromised hosts. Here, we present an immunocompetent adult with greenish-black discoloration of the right first finger nail in combination with recurrent onycholysis. C. parapsilosis was isolated from the righ...

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Detalles Bibliográficos
Autores principales: Ge, Gai, Yang, Zhiya, Li, Dongmei, Sybren de Hoog, G., Shi, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476797/
https://www.ncbi.nlm.nih.gov/pubmed/31024790
http://dx.doi.org/10.1016/j.mmcr.2019.04.005
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author Ge, Gai
Yang, Zhiya
Li, Dongmei
Sybren de Hoog, G.
Shi, Dongmei
author_facet Ge, Gai
Yang, Zhiya
Li, Dongmei
Sybren de Hoog, G.
Shi, Dongmei
author_sort Ge, Gai
collection PubMed
description Candida parapsilosis (C. parapsilosis) has become a common pathogen, especially in immunocompromised hosts. Here, we present an immunocompetent adult with greenish-black discoloration of the right first finger nail in combination with recurrent onycholysis. C. parapsilosis was isolated from the right first finger nail and was confirmed by morphological characteristics as well as by DNA molecular analysis. Patient was successfully treated with oral itraconazole in a regimen of 5 cycles of 200 mg twice daily for one week, followed by an interruption of treatment for 3 weeks. To our knowledge, this is the first report of C. parapsilosis-induced onychomycosis with recurrent onycholysis.
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spelling pubmed-64767972019-04-25 Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis Ge, Gai Yang, Zhiya Li, Dongmei Sybren de Hoog, G. Shi, Dongmei Med Mycol Case Rep Case Report Candida parapsilosis (C. parapsilosis) has become a common pathogen, especially in immunocompromised hosts. Here, we present an immunocompetent adult with greenish-black discoloration of the right first finger nail in combination with recurrent onycholysis. C. parapsilosis was isolated from the right first finger nail and was confirmed by morphological characteristics as well as by DNA molecular analysis. Patient was successfully treated with oral itraconazole in a regimen of 5 cycles of 200 mg twice daily for one week, followed by an interruption of treatment for 3 weeks. To our knowledge, this is the first report of C. parapsilosis-induced onychomycosis with recurrent onycholysis. Elsevier 2019-04-16 /pmc/articles/PMC6476797/ /pubmed/31024790 http://dx.doi.org/10.1016/j.mmcr.2019.04.005 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ge, Gai
Yang, Zhiya
Li, Dongmei
Sybren de Hoog, G.
Shi, Dongmei
Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis
title Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis
title_full Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis
title_fullStr Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis
title_full_unstemmed Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis
title_short Onychomycosis with greenish-black discolorations and recurrent onycholysis caused by Candida parapsilosis
title_sort onychomycosis with greenish-black discolorations and recurrent onycholysis caused by candida parapsilosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476797/
https://www.ncbi.nlm.nih.gov/pubmed/31024790
http://dx.doi.org/10.1016/j.mmcr.2019.04.005
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