Cargando…
Ancestral Stress Alters Lifetime Mental Health Trajectories and Cortical Neuromorphology via Epigenetic Regulation
Experiences during early development are powerful determinants of lifetime mental health. Here we investigated if ancestral stress regulates the brain’s epigenetic memory to alter neuromorphology and emotionality in the remote F4 progeny. Pregnant female rat dams of the parental F0 generation were e...
Autores principales: | Ambeskovic, Mirela, Babenko, Olena, Ilnytskyy, Yaroslav, Kovalchuk, Igor, Kolb, Bryan, Metz, Gerlinde A. S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476877/ https://www.ncbi.nlm.nih.gov/pubmed/31011159 http://dx.doi.org/10.1038/s41598-019-42691-z |
Ejemplares similares
-
Ancestral stress programs sex-specific biological aging trajectories and non-communicable disease risk
por: Ambeskovic, Mirela, et al.
Publicado: (2020) -
Genomic and Epigenomic Responses to Chronic Stress Involve miRNA-Mediated Programming
por: Babenko, Olena, et al.
Publicado: (2012) -
Immunosenescence is associated with altered gene expression and epigenetic regulation in primary and secondary immune organs
por: Sidler, Corinne, et al.
Publicado: (2013) -
Evidence for Ancestral Programming of Resilience in a Two-Hit Stress Model
por: Faraji, Jamshid, et al.
Publicado: (2017) -
Environmental Intervention as a Therapy for Adverse Programming by Ancestral Stress
por: McCreary, J. Keiko, et al.
Publicado: (2016)