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Analysis of AMB-FUBINACA Biotransformation Pathways in Human Liver Microsome and Zebrafish Systems by Liquid Chromatography-High Resolution Mass Spectrometry

In this study, the metabolic profiles of a new illicit drug AMB-FUBINACA were investigated using both human liver microsome and zebrafish models. Liquid chromatography Q Extractive HF Hybrid Quadrupole-Orbitrap mass spectrometry (LC-QE-HF-MS) was employed to analyze the metabolic sites and pathways....

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Detalles Bibliográficos
Autores principales:	Xu, Duo-qi, Zhang, Wen-fang, Li, Jing, Wang, Ji-fen, Qin, Shi-yang, Lu, Jiang-hai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476901/ https://www.ncbi.nlm.nih.gov/pubmed/31041306 http://dx.doi.org/10.3389/fchem.2019.00240

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