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The Systemic Administration of the Histamine H(1) Receptor Antagonist/Inverse Agonist Chlorpheniramine to Pregnant Rats Impairs the Development of Nigro-Striatal Dopaminergic Neurons

The dopaminergic and histaminergic systems are the first to appear during the development of the nervous system. Through the activation of H(1) receptors (H(1)Rs), histamine increases neurogenesis of the cortical deep layers, while reducing the dopaminergic phenotype (cells immunoreactive to tyrosin...

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Detalles Bibliográficos
Autores principales: Márquez-Valadez, Berenice, Aquino-Miranda, Guillermo, Quintero-Romero, Mijail-Oliver, Papacostas-Quintanilla, Helena, Bueno-Nava, Antonio, López-Rubalcava, Carolina, Díaz, Néstor Fabián, Arias-Montaño, José-Antonio, Molina-Hernández, Anayansi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476962/
https://www.ncbi.nlm.nih.gov/pubmed/31040765
http://dx.doi.org/10.3389/fnins.2019.00360

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