The CXXC Motifs Are Essential for the Function of BosR in Borrelia burgdorferi

BosR, a Fur family member, is essential for the pathogenesis of the Lyme disease pathogen, Borrelia burgdorferi. Unlike typical Fur proteins in which DNA binding represses gene expression, binding of BosR to the rpoS promoter directly activates rpoS transcription in B. burgdorferi. However, virtuall...

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Detalles Bibliográficos
Autores principales: Mason, Charlotte, Liu, Xiaoyan, Prabhudeva, Spoorthy, Ouyang, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476982/
https://www.ncbi.nlm.nih.gov/pubmed/31041197
http://dx.doi.org/10.3389/fcimb.2019.00109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476982/
https://www.ncbi.nlm.nih.gov/pubmed/31041197
http://dx.doi.org/10.3389/fcimb.2019.00109

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