Intranasal Administration of Extracellular Vesicles Derived from Human Teeth Stem Cells Improves Motor Symptoms and Normalizes Tyrosine Hydroxylase Expression in the Substantia Nigra and Striatum of the 6‐Hydroxydopamine‐Treated Rats

Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting millions of people worldwide. At present, there is no effective cure for PD; treatments are symptomatic and do not halt progression of neurodegeneration. Extracellular vesicles (EVs) can cross the blood–brai...

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Detalles Bibliográficos
Autores principales: Narbute, Karīna, Piļipenko, Vladimirs, Pupure, Jolanta, Dzirkale, Zane, Jonavičė, Ugnė, Tunaitis, Virginijus, Kriaučiūnaitė, Karolina, Jarmalavičiūtė, Akvilė, Jansone, Baiba, Kluša, Vija, Pivoriūnas, Augustas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Tissue Engineering and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477008/
https://www.ncbi.nlm.nih.gov/pubmed/30706999
http://dx.doi.org/10.1002/sctm.18-0162

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