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Molecular Adaptations in the Rat Dorsal Striatum and Hippocampus Following Abstinence-Induced Incubation of Drug Seeking After Escalated Oxycodone Self-Administration

Repeated exposure to the opioid agonist, oxycodone, can lead to addiction. Here, we sought to identify potential neurobiological consequences of withdrawal from escalated and non-escalated oxycodone self-administration in rats. To reach these goals, we used short-access (ShA) (3 h) and long-access (...

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Detalles Bibliográficos
Autores principales: Blackwood, Christopher A., Hoerle, Reece, Leary, Michael, Schroeder, Jennifer, Job, Martin O., McCoy, Michael T., Ladenheim, Bruce, Jayanthi, Subramaniam, Cadet, Jean Lud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477015/
https://www.ncbi.nlm.nih.gov/pubmed/30155791
http://dx.doi.org/10.1007/s12035-018-1318-z