NFκB and Kidney Injury

The global burden of chronic kidney disease will increase during the next century. As NFκB, first described more than 30 years ago, plays a major role in immune and non-immune-mediated diseases and in inflammatory and metabolic disorders, this review article summarizes current knowledge on the role...

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Detalles Bibliográficos
Autores principales: Song, Ning, Thaiss, Friedrich, Guo, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477040/
https://www.ncbi.nlm.nih.gov/pubmed/31040851
http://dx.doi.org/10.3389/fimmu.2019.00815
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author Song, Ning
Thaiss, Friedrich
Guo, Linlin
author_facet Song, Ning
Thaiss, Friedrich
Guo, Linlin
author_sort Song, Ning
collection PubMed
description The global burden of chronic kidney disease will increase during the next century. As NFκB, first described more than 30 years ago, plays a major role in immune and non-immune-mediated diseases and in inflammatory and metabolic disorders, this review article summarizes current knowledge on the role of NFκB in in vivo kidney injury and describes the new and so far not completely understood crosstalk between canonical and non-canonical NFκB pathways in T-lymphocyte activation in renal disease.
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spelling pubmed-64770402019-04-30 NFκB and Kidney Injury Song, Ning Thaiss, Friedrich Guo, Linlin Front Immunol Immunology The global burden of chronic kidney disease will increase during the next century. As NFκB, first described more than 30 years ago, plays a major role in immune and non-immune-mediated diseases and in inflammatory and metabolic disorders, this review article summarizes current knowledge on the role of NFκB in in vivo kidney injury and describes the new and so far not completely understood crosstalk between canonical and non-canonical NFκB pathways in T-lymphocyte activation in renal disease. Frontiers Media S.A. 2019-04-16 /pmc/articles/PMC6477040/ /pubmed/31040851 http://dx.doi.org/10.3389/fimmu.2019.00815 Text en Copyright © 2019 Song, Thaiss and Guo. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Immunology
Song, Ning
Thaiss, Friedrich
Guo, Linlin
NFκB and Kidney Injury
title NFκB and Kidney Injury
title_full NFκB and Kidney Injury
title_fullStr NFκB and Kidney Injury
title_full_unstemmed NFκB and Kidney Injury
title_short NFκB and Kidney Injury
title_sort nfκb and kidney injury
topic Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477040/
https://www.ncbi.nlm.nih.gov/pubmed/31040851
http://dx.doi.org/10.3389/fimmu.2019.00815
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AT thaissfriedrich nfkbandkidneyinjury
AT guolinlin nfkbandkidneyinjury

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