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Canagliflozin Inhibits Human Endothelial Cell Proliferation and Tube Formation

Recent clinical trials revealed that sodium-glucose co-transporter 2 (SGLT2) inhibitors significantly reduce cardiovascular events in type 2 diabetic patients, however, canagliflozin increased limb amputations, an effect not seen with other SGLT2 inhibitors. Since endothelial cell (EC) dysfunction p...

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Detalles Bibliográficos
Autores principales:	Behnammanesh, Ghazaleh, Durante, Zane E., Peyton, Kelly J., Martinez-Lemus, Luis A., Brown, Scott M., Bender, Shawn B., Durante, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477081/ https://www.ncbi.nlm.nih.gov/pubmed/31057401 http://dx.doi.org/10.3389/fphar.2019.00362

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