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Design, synthesis and biological evaluation of selective survivin inhibitors

The differential distribution between cancer cells and normal adult tissues makes survivin a very attractive cancer drug target. We have previously reported a series of novel selective survivin inhibitors with the most potent compound MX106 reaching nanomolar activity in several cancer cell lines. F...

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Detalles Bibliográficos
Autores principales:	Xiao, Min, Xue, Yi, Wu, Zhongzhi, Lei, Zi-Ning, Wang, Jin, Chen, Zhe-Sheng, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477172/ https://www.ncbi.nlm.nih.gov/pubmed/30174320 http://dx.doi.org/10.7555/JBR.31.20160173

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