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Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas()
BACKGROUND: Ependymomas (EPNs) are the third most common brain tumor in children. These tumors are resistant to available chemotherapeutic treatments, therefore new effective targeted therapeutics must be identified. Increasing evidence shows epigenetic alterations including histone posttranslationa...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477190/ https://www.ncbi.nlm.nih.gov/pubmed/31005631 http://dx.doi.org/10.1016/j.neo.2019.03.012 |