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Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse?
Purpose: Lung cancer is one of the major sources of mortality in the elderly. This study was undertaken to assess the early and long-term results of surgical resection in patients older than 70 years of age by comparing the results of patients aged 70–79 years (group 1) with patients older than 80 y...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477457/ https://www.ncbi.nlm.nih.gov/pubmed/30542000 http://dx.doi.org/10.5761/atcs.oa.18-00206 |
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author | Kutluk, Ali Cevat Akin, Hasan Ceritoglu, Altan Kocaturk, Celalettin Ibrahim Bilen, Salih Sonmezoglu, Yasar Karapinar, Kemal |
author_facet | Kutluk, Ali Cevat Akin, Hasan Ceritoglu, Altan Kocaturk, Celalettin Ibrahim Bilen, Salih Sonmezoglu, Yasar Karapinar, Kemal |
author_sort | Kutluk, Ali Cevat |
collection | PubMed |
description | Purpose: Lung cancer is one of the major sources of mortality in the elderly. This study was undertaken to assess the early and long-term results of surgical resection in patients older than 70 years of age by comparing the results of patients aged 70–79 years (group 1) with patients older than 80 years of age (group 2). Methods: Data on patient age, gender, spirometry values, side, size, histology and stage of the tumor, surgical procedures, postoperative complications, Charlson comorbidity scores (CCS), and survival were collected. Results: After 1–2 propensity score matching group 1 (70–79 years) included 84 and group 2 (age over 80) 42 cases. The multivariate analysis showed that CCS was the only significant factor affecting the development of complications (p = 0.003). The overall median and 5-year survival of all patients were 55 months and 42.5%, respectively. Although the survival of the elderly group 2 was higher than the first group, the difference did not reach significance (50 vs. 49 months, respectively). Conclusion: The outcomes of surgery in terms of morbidity and mortality rates do not differ between the two age groups. The safety of pulmonary resections in the elderly group is comparable to patients under 70 years if the comorbidities are appropriately controlled. In addition, surgery provides satisfactory survival rates in both age groups. |
format | Online Article Text |
id | pubmed-6477457 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-64774572019-04-23 Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse? Kutluk, Ali Cevat Akin, Hasan Ceritoglu, Altan Kocaturk, Celalettin Ibrahim Bilen, Salih Sonmezoglu, Yasar Karapinar, Kemal Ann Thorac Cardiovasc Surg Original Article Purpose: Lung cancer is one of the major sources of mortality in the elderly. This study was undertaken to assess the early and long-term results of surgical resection in patients older than 70 years of age by comparing the results of patients aged 70–79 years (group 1) with patients older than 80 years of age (group 2). Methods: Data on patient age, gender, spirometry values, side, size, histology and stage of the tumor, surgical procedures, postoperative complications, Charlson comorbidity scores (CCS), and survival were collected. Results: After 1–2 propensity score matching group 1 (70–79 years) included 84 and group 2 (age over 80) 42 cases. The multivariate analysis showed that CCS was the only significant factor affecting the development of complications (p = 0.003). The overall median and 5-year survival of all patients were 55 months and 42.5%, respectively. Although the survival of the elderly group 2 was higher than the first group, the difference did not reach significance (50 vs. 49 months, respectively). Conclusion: The outcomes of surgery in terms of morbidity and mortality rates do not differ between the two age groups. The safety of pulmonary resections in the elderly group is comparable to patients under 70 years if the comorbidities are appropriately controlled. In addition, surgery provides satisfactory survival rates in both age groups. The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery 2018-12-11 2019 /pmc/articles/PMC6477457/ /pubmed/30542000 http://dx.doi.org/10.5761/atcs.oa.18-00206 Text en ©2019 Annals of Thoracic and Cardiovascular Surgery http://creativecommons.org/licenses/by-nc-nd/4.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NonDerivatives International License (http://creativecommons.org/licenses/by-nc-nd/4.0/) |
spellingShingle | Original Article Kutluk, Ali Cevat Akin, Hasan Ceritoglu, Altan Kocaturk, Celalettin Ibrahim Bilen, Salih Sonmezoglu, Yasar Karapinar, Kemal Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse? |
title | Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse? |
title_full | Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse? |
title_fullStr | Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse? |
title_full_unstemmed | Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse? |
title_short | Is the Outcome of Pulmonary Resections due to Non-Small Cell Lung Cancer in Octogenarian Patients Worse? |
title_sort | is the outcome of pulmonary resections due to non-small cell lung cancer in octogenarian patients worse? |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477457/ https://www.ncbi.nlm.nih.gov/pubmed/30542000 http://dx.doi.org/10.5761/atcs.oa.18-00206 |
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