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Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report

INTRODUCTION: Giant cell tumors (GCT) are benign lesions that are generally locally aggressive tumors with occasional malignant behavior. These tumors are most frequently encountered in long bones; however, they also occur rarely in the spine. GCT of the spine are rare pathological entities, and spi...

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Autores principales: Al-Shamary, Eid, Al-Dhafeeri, Wafa, Al-Sharydah, Abdulaziz, Al-Suhibani, Sari, Kussaibi, Haitham, Al-Issawi, Wisam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477464/
https://www.ncbi.nlm.nih.gov/pubmed/31043951
http://dx.doi.org/10.1159/000497379
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author Al-Shamary, Eid
Al-Dhafeeri, Wafa
Al-Sharydah, Abdulaziz
Al-Suhibani, Sari
Kussaibi, Haitham
Al-Issawi, Wisam
author_facet Al-Shamary, Eid
Al-Dhafeeri, Wafa
Al-Sharydah, Abdulaziz
Al-Suhibani, Sari
Kussaibi, Haitham
Al-Issawi, Wisam
author_sort Al-Shamary, Eid
collection PubMed
description INTRODUCTION: Giant cell tumors (GCT) are benign lesions that are generally locally aggressive tumors with occasional malignant behavior. These tumors are most frequently encountered in long bones; however, they also occur rarely in the spine. GCT of the spine are rare pathological entities, and spinal involvement shows a sacral predilection, with only a few cases involving the supra-sacral segment (mobile spine). Only a few cases of thoracic spinal GCT are reported in the literature; these tumors are particularly uncommon in the thoracic segment. PRESENTATION OF CASE: A 29-year-old man presented with a complaint of neck pain over the previous six months that radiated to his left hand. GCT of the upper thoracic spine was diagnosed, which was surgically managed using a 2-stage approach involving total resection of the tumor followed by spondylectomy and multilevel spinal fixation. DISCUSSION: Accurate diagnosis of vertebral column lesions, and choosing an optimum management plan are crucial. In the majority of cases, En-bloc resection of GCTs is not feasible ought to the close contact of the lesion with the spinal cord. Larger studies are encouraged to ascertain the efficacy of variable management approaches, particularly compared with piecemeal resection techniques. CONCLUSION: Spinal GCT are a unique group of tumors with an uncommon and unexpected presentation. Although surgery is the mainstay of treatment for spinal GCT, the management of this tumor can be challenging. No clear management algorithm has been established, and the tumor displays an unpredictable course. Therefore, each case needs tailored treatment.
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spelling pubmed-64774642019-05-01 Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report Al-Shamary, Eid Al-Dhafeeri, Wafa Al-Sharydah, Abdulaziz Al-Suhibani, Sari Kussaibi, Haitham Al-Issawi, Wisam Case Rep Oncol Case Report INTRODUCTION: Giant cell tumors (GCT) are benign lesions that are generally locally aggressive tumors with occasional malignant behavior. These tumors are most frequently encountered in long bones; however, they also occur rarely in the spine. GCT of the spine are rare pathological entities, and spinal involvement shows a sacral predilection, with only a few cases involving the supra-sacral segment (mobile spine). Only a few cases of thoracic spinal GCT are reported in the literature; these tumors are particularly uncommon in the thoracic segment. PRESENTATION OF CASE: A 29-year-old man presented with a complaint of neck pain over the previous six months that radiated to his left hand. GCT of the upper thoracic spine was diagnosed, which was surgically managed using a 2-stage approach involving total resection of the tumor followed by spondylectomy and multilevel spinal fixation. DISCUSSION: Accurate diagnosis of vertebral column lesions, and choosing an optimum management plan are crucial. In the majority of cases, En-bloc resection of GCTs is not feasible ought to the close contact of the lesion with the spinal cord. Larger studies are encouraged to ascertain the efficacy of variable management approaches, particularly compared with piecemeal resection techniques. CONCLUSION: Spinal GCT are a unique group of tumors with an uncommon and unexpected presentation. Although surgery is the mainstay of treatment for spinal GCT, the management of this tumor can be challenging. No clear management algorithm has been established, and the tumor displays an unpredictable course. Therefore, each case needs tailored treatment. S. Karger AG 2019-02-08 /pmc/articles/PMC6477464/ /pubmed/31043951 http://dx.doi.org/10.1159/000497379 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Al-Shamary, Eid
Al-Dhafeeri, Wafa
Al-Sharydah, Abdulaziz
Al-Suhibani, Sari
Kussaibi, Haitham
Al-Issawi, Wisam
Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report
title Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report
title_full Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report
title_fullStr Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report
title_full_unstemmed Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report
title_short Total Spondylectomy for Upper Thoracic Spine Giant Cell Tumor: A Case Report
title_sort total spondylectomy for upper thoracic spine giant cell tumor: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477464/
https://www.ncbi.nlm.nih.gov/pubmed/31043951
http://dx.doi.org/10.1159/000497379
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