Purinergic Signaling in the Vertebrate Olfactory System

Adenosine 5′-triphosphate (ATP) is an ubiquitous co-transmitter in the vertebrate brain. ATP itself, as well as its breakdown products ADP and adenosine are involved in synaptic transmission and plasticity, neuron-glia communication and neural development. Although purinoceptors have been demonstrat...

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Autores principales: Rotermund, Natalie, Schulz, Kristina, Hirnet, Daniela, Lohr, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477478/
https://www.ncbi.nlm.nih.gov/pubmed/31057369
http://dx.doi.org/10.3389/fncel.2019.00112
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author Rotermund, Natalie
Schulz, Kristina
Hirnet, Daniela
Lohr, Christian
author_facet Rotermund, Natalie
Schulz, Kristina
Hirnet, Daniela
Lohr, Christian
author_sort Rotermund, Natalie
collection PubMed
description Adenosine 5′-triphosphate (ATP) is an ubiquitous co-transmitter in the vertebrate brain. ATP itself, as well as its breakdown products ADP and adenosine are involved in synaptic transmission and plasticity, neuron-glia communication and neural development. Although purinoceptors have been demonstrated in the vertebrate olfactory system by means of histological techniques for many years, detailed insights into physiological properties and functional significance of purinergic signaling in olfaction have been published only recently. We review the current literature on purinergic neuromodulation, neuron-glia interactions and neurogenesis in the vertebrate olfactory system.
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spelling pubmed-64774782019-05-03 Purinergic Signaling in the Vertebrate Olfactory System Rotermund, Natalie Schulz, Kristina Hirnet, Daniela Lohr, Christian Front Cell Neurosci Neuroscience Adenosine 5′-triphosphate (ATP) is an ubiquitous co-transmitter in the vertebrate brain. ATP itself, as well as its breakdown products ADP and adenosine are involved in synaptic transmission and plasticity, neuron-glia communication and neural development. Although purinoceptors have been demonstrated in the vertebrate olfactory system by means of histological techniques for many years, detailed insights into physiological properties and functional significance of purinergic signaling in olfaction have been published only recently. We review the current literature on purinergic neuromodulation, neuron-glia interactions and neurogenesis in the vertebrate olfactory system. Frontiers Media S.A. 2019-04-16 /pmc/articles/PMC6477478/ /pubmed/31057369 http://dx.doi.org/10.3389/fncel.2019.00112 Text en Copyright © 2019 Rotermund, Schulz, Hirnet and Lohr. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Rotermund, Natalie
Schulz, Kristina
Hirnet, Daniela
Lohr, Christian
Purinergic Signaling in the Vertebrate Olfactory System
title Purinergic Signaling in the Vertebrate Olfactory System
title_full Purinergic Signaling in the Vertebrate Olfactory System
title_fullStr Purinergic Signaling in the Vertebrate Olfactory System
title_full_unstemmed Purinergic Signaling in the Vertebrate Olfactory System
title_short Purinergic Signaling in the Vertebrate Olfactory System
title_sort purinergic signaling in the vertebrate olfactory system
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477478/
https://www.ncbi.nlm.nih.gov/pubmed/31057369
http://dx.doi.org/10.3389/fncel.2019.00112
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AT lohrchristian purinergicsignalinginthevertebrateolfactorysystem

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