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Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia

Hemolytic anemia in the setting of malignancy is a rare manifestation of paraneoplastic syndrome with significant morbidity. Here we discuss a case involving metastatic breast cancer presenting with severe hemolytic anemia and renal failure secondary to thrombotic microangiopathy of malignancy. This...

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Autores principales: Lee, Eric H., Otoukesh, Salman, Abdi pour, Amir, Nagaraj, Gayathri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477541/
https://www.ncbi.nlm.nih.gov/pubmed/31043946
http://dx.doi.org/10.1159/000494753
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author Lee, Eric H.
Otoukesh, Salman
Abdi pour, Amir
Nagaraj, Gayathri
author_facet Lee, Eric H.
Otoukesh, Salman
Abdi pour, Amir
Nagaraj, Gayathri
author_sort Lee, Eric H.
collection PubMed
description Hemolytic anemia in the setting of malignancy is a rare manifestation of paraneoplastic syndrome with significant morbidity. Here we discuss a case involving metastatic breast cancer presenting with severe hemolytic anemia and renal failure secondary to thrombotic microangiopathy of malignancy. This case discusses the workup for secondary hemolytic anemia, a possible role for therapeutic plasma exchange in this setting, as well the current understanding of the management of microangiopathic hemolytic anemia of malignancy.
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spelling pubmed-64775412019-05-01 Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia Lee, Eric H. Otoukesh, Salman Abdi pour, Amir Nagaraj, Gayathri Case Rep Oncol Case Report Hemolytic anemia in the setting of malignancy is a rare manifestation of paraneoplastic syndrome with significant morbidity. Here we discuss a case involving metastatic breast cancer presenting with severe hemolytic anemia and renal failure secondary to thrombotic microangiopathy of malignancy. This case discusses the workup for secondary hemolytic anemia, a possible role for therapeutic plasma exchange in this setting, as well the current understanding of the management of microangiopathic hemolytic anemia of malignancy. S. Karger AG 2019-01-23 /pmc/articles/PMC6477541/ /pubmed/31043946 http://dx.doi.org/10.1159/000494753 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Lee, Eric H.
Otoukesh, Salman
Abdi pour, Amir
Nagaraj, Gayathri
Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia
title Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia
title_full Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia
title_fullStr Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia
title_full_unstemmed Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia
title_short Hemolytic Anemia of Malignancy: A Case Study Involving Signet Ring Cell Metastatic Breast Cancer with Severe Microangiopathic Hemolytic Anemia
title_sort hemolytic anemia of malignancy: a case study involving signet ring cell metastatic breast cancer with severe microangiopathic hemolytic anemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477541/
https://www.ncbi.nlm.nih.gov/pubmed/31043946
http://dx.doi.org/10.1159/000494753
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