Cargando…

Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems

Background: Insulin pumps are used for basal rate and bolus insulin delivery in patients with diabetes. In this in vitro study, accuracy of delivery of different commercial insulin pumps was evaluated. Materials and Methods: Accuracy of 10 different insulin pump systems (5 durable pumps with differe...

Descripción completa

Detalles Bibliográficos
Autores principales: Freckmann, Guido, Kamecke, Ulrike, Waldenmaier, Delia, Haug, Cornelia, Ziegler, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477586/
https://www.ncbi.nlm.nih.gov/pubmed/30901232
http://dx.doi.org/10.1089/dia.2018.0376
_version_ 1783413043750764544
author Freckmann, Guido
Kamecke, Ulrike
Waldenmaier, Delia
Haug, Cornelia
Ziegler, Ralph
author_facet Freckmann, Guido
Kamecke, Ulrike
Waldenmaier, Delia
Haug, Cornelia
Ziegler, Ralph
author_sort Freckmann, Guido
collection PubMed
description Background: Insulin pumps are used for basal rate and bolus insulin delivery in patients with diabetes. In this in vitro study, accuracy of delivery of different commercial insulin pumps was evaluated. Materials and Methods: Accuracy of 10 different insulin pump systems (5 durable pumps with different insulin infusion sets and 1 patch pump) was tested with a microgravimetric method. Mean bolus accuracy of 25 successive 1 U boluses and of 12 successive 10 U boluses was assessed, and delivery time for 10 U boluses was measured. Basal rate accuracy at 1.0 U/h was evaluated for 72 h and for individual 1-h windows. Results: Mean bolus delivery was within ±5% of target for both tested bolus sizes, but precision of individual boluses was higher with the larger boluses. Delivery times varied between the different pump models but agreed with the specifications of the respective manufacturers. Regarding basal rate accuracy, the total deviation for 72 h was very small in all pumps; however, larger deviations were observed during the first 12 h. For the patch pump, large variations between individual 1-h windows were observed. Conclusions: In general, all compared insulin pump systems showed a similar level of accuracy. Differences, especially between durable pumps and the patch pump, were observed when considering each hour of basal rate delivery separately.
format Online
Article
Text
id pubmed-6477586
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Mary Ann Liebert, Inc., publishers
record_format MEDLINE/PubMed
spelling pubmed-64775862019-04-23 Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems Freckmann, Guido Kamecke, Ulrike Waldenmaier, Delia Haug, Cornelia Ziegler, Ralph Diabetes Technol Ther Original Articles Background: Insulin pumps are used for basal rate and bolus insulin delivery in patients with diabetes. In this in vitro study, accuracy of delivery of different commercial insulin pumps was evaluated. Materials and Methods: Accuracy of 10 different insulin pump systems (5 durable pumps with different insulin infusion sets and 1 patch pump) was tested with a microgravimetric method. Mean bolus accuracy of 25 successive 1 U boluses and of 12 successive 10 U boluses was assessed, and delivery time for 10 U boluses was measured. Basal rate accuracy at 1.0 U/h was evaluated for 72 h and for individual 1-h windows. Results: Mean bolus delivery was within ±5% of target for both tested bolus sizes, but precision of individual boluses was higher with the larger boluses. Delivery times varied between the different pump models but agreed with the specifications of the respective manufacturers. Regarding basal rate accuracy, the total deviation for 72 h was very small in all pumps; however, larger deviations were observed during the first 12 h. For the patch pump, large variations between individual 1-h windows were observed. Conclusions: In general, all compared insulin pump systems showed a similar level of accuracy. Differences, especially between durable pumps and the patch pump, were observed when considering each hour of basal rate delivery separately. Mary Ann Liebert, Inc., publishers 2019-04-01 2019-03-30 /pmc/articles/PMC6477586/ /pubmed/30901232 http://dx.doi.org/10.1089/dia.2018.0376 Text en © Guido Freckmann, et al., 2019; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Original Articles
Freckmann, Guido
Kamecke, Ulrike
Waldenmaier, Delia
Haug, Cornelia
Ziegler, Ralph
Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems
title Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems
title_full Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems
title_fullStr Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems
title_full_unstemmed Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems
title_short Accuracy of Bolus and Basal Rate Delivery of Different Insulin Pump Systems
title_sort accuracy of bolus and basal rate delivery of different insulin pump systems
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477586/
https://www.ncbi.nlm.nih.gov/pubmed/30901232
http://dx.doi.org/10.1089/dia.2018.0376
work_keys_str_mv AT freckmannguido accuracyofbolusandbasalratedeliveryofdifferentinsulinpumpsystems
AT kameckeulrike accuracyofbolusandbasalratedeliveryofdifferentinsulinpumpsystems
AT waldenmaierdelia accuracyofbolusandbasalratedeliveryofdifferentinsulinpumpsystems
AT haugcornelia accuracyofbolusandbasalratedeliveryofdifferentinsulinpumpsystems
AT zieglerralph accuracyofbolusandbasalratedeliveryofdifferentinsulinpumpsystems