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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
Adjustment of cerebral blood flow (CBF) to neuronal activity via neurovascular coupling (NVC) has an essential role in maintenance of healthy cognitive function. In aging increased oxidative stress and cerebromicrovascular endothelial dysfunction impair NVC, contributing to cognitive decline. There...
Autores principales: | Tarantini, Stefano, Valcarcel-Ares, Marta Noa, Toth, Peter, Yabluchanskiy, Andriy, Tucsek, Zsuzsanna, Kiss, Tamas, Hertelendy, Peter, Kinter, Michael, Ballabh, Praveen, Süle, Zoltán, Farkas, Eszter, Baur, Joseph A., Sinclair, David A., Csiszar, Anna, Ungvari, Zoltan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477631/ https://www.ncbi.nlm.nih.gov/pubmed/31015147 http://dx.doi.org/10.1016/j.redox.2019.101192 |
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