Cargando…
Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains
Throughout metazoans, Staufen (Stau) proteins are core factors of mRNA localization particles. They consist of three to four double-stranded RNA binding domains (dsRBDs) and a C-terminal dsRBD-like domain. Mouse Staufen2 (mStau2)-like Drosophila Stau (dmStau) contains four dsRBDs. Existing data sugg...
Autores principales: | Heber, Simone, Gáspár, Imre, Tants, Jan-Niklas, Günther, Johannes, Moya, Sandra M. Fernandez, Janowski, Robert, Ephrussi, Anne, Sattler, Michael, Niessing, Dierk |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477676/ https://www.ncbi.nlm.nih.gov/pubmed/30971701 http://dx.doi.org/10.1038/s41467-019-09655-3 |
Ejemplares similares
-
Structural basis for the recognition of transiently structured AU-rich elements by Roquin
por: Binas, Oliver, et al.
Publicado: (2020) -
The large family of PC4-like domains – similar folds and functions throughout all kingdoms of life
por: Janowski, Robert, et al.
Publicado: (2020) -
Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
por: Schneider, Tim, et al.
Publicado: (2019) -
Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator
por: Schlundt, Andreas, et al.
Publicado: (2017) -
Crystal and solution structural studies of mouse phospholipid hydroperoxide glutathione peroxidase 4
por: Janowski, Robert, et al.
Publicado: (2016)