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Evolutionary engineering in Saccharomyces cerevisiae reveals a TRK1-dependent potassium influx mechanism for propionic acid tolerance
BACKGROUND: Propionic acid (PA), a key platform chemical produced as a by-product during petroleum refining, has been widely used as a food preservative and an important chemical intermediate in many industries. Microbial PA production through engineering yeast as a cell factory is a potentially sus...
Autores principales: | Xu, Xin, Williams, Thomas C., Divne, Christina, Pretorius, Isak S., Paulsen, Ian T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477708/ https://www.ncbi.nlm.nih.gov/pubmed/31044010 http://dx.doi.org/10.1186/s13068-019-1427-6 |
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