Complement protein levels in plasma astrocyte-derived exosomes are abnormal in conversion from mild cognitive impairment to Alzheimer's disease dementia

INTRODUCTION: Levels of complement proteins (CPs) in plasma astrocyte-derived exosomes (ADEs) that are abnormal in Alzheimer's disease (AD) have not been assessed in mild cognitive impairment (MCI). METHODS: Participants (n = 20 per group) had either MCI converting to dementia within 3 years (M...

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Detalles Bibliográficos
Autores principales: Winston, Charisse N., Goetzl, Edward J., Schwartz, Janice B., Elahi, Fanny M., Rissman, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Special Section: Blood-Based Biomarkers for Alzheimer's Disease & Related Dementias. (Editor: Henrik Zetterberg)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477776/
https://www.ncbi.nlm.nih.gov/pubmed/31032394
http://dx.doi.org/10.1016/j.dadm.2018.11.002

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