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A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

Transgenic malaria parasites expressing fluorescent and bioluminescent proteins are valuable tools to interrogate malaria-parasite biology and to evaluate drugs and vaccines. Using CRISPR/Cas9 methodology a transgenic Plasmodium falciparum (Pf) NF54 line was generated that expresses a fusion of mChe...

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Detalles Bibliográficos
Autores principales: Marin-Mogollon, Catherin, Salman, Ahmed M., Koolen, Karin M. J., Bolscher, Judith M., van Pul, Fiona J. A., Miyazaki, Shinya, Imai, Takashi, Othman, Ahmad Syibli, Ramesar, Jai, van Gemert, Geert-Jan, Kroeze, Hans, Chevalley-Maurel, Severine, Franke-Fayard, Blandine, Sauerwein, Robert W., Hill, Adrian V. S., Dechering, Koen J., Janse, Chris J., Khan, Shahid M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477837/
https://www.ncbi.nlm.nih.gov/pubmed/31058097
http://dx.doi.org/10.3389/fcimb.2019.00096