Cargando…

A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

Transgenic malaria parasites expressing fluorescent and bioluminescent proteins are valuable tools to interrogate malaria-parasite biology and to evaluate drugs and vaccines. Using CRISPR/Cas9 methodology a transgenic Plasmodium falciparum (Pf) NF54 line was generated that expresses a fusion of mChe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marin-Mogollon, Catherin, Salman, Ahmed M., Koolen, Karin M. J., Bolscher, Judith M., van Pul, Fiona J. A., Miyazaki, Shinya, Imai, Takashi, Othman, Ahmad Syibli, Ramesar, Jai, van Gemert, Geert-Jan, Kroeze, Hans, Chevalley-Maurel, Severine, Franke-Fayard, Blandine, Sauerwein, Robert W., Hill, Adrian V. S., Dechering, Koen J., Janse, Chris J., Khan, Shahid M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477837/ https://www.ncbi.nlm.nih.gov/pubmed/31058097 http://dx.doi.org/10.3389/fcimb.2019.00096

Ejemplares similares

Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites
por: Marin-Mogollon, Catherin, et al.
Publicado: (2018)

The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission
por: Marin-Mogollon, Catherin, et al.
Publicado: (2018)

Author Correction: The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission
por: Marin-Mogollon, Catherin, et al.
Publicado: (2019)

Rapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection Protocol
por: Mogollon, Catherin Marin, et al.
Publicado: (2016)

OX40 Stimulation Enhances Protective Immune Responses Induced After Vaccination With Attenuated Malaria Parasites
por: Othman, Ahmad Syibli, et al.
Publicado: (2018)

Screening of viral-vectored P. falciparum pre-erythrocytic candidate vaccine antigens using chimeric rodent parasites
por: Kolli, Surendra Kumar, et al.
Publicado: (2021)

Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening
por: Miglianico, Marie, et al.
Publicado: (2023)

Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum
por: Wang, Christian W, et al.
Publicado: (2010)

Generation of Novel Plasmodium falciparum NF135 and NF54 Lines Expressing Fluorescent Reporter Proteins Under the Control of Strong and Constitutive Promoters
por: Miyazaki, Shinya, et al.
Publicado: (2020)

Generation of a Genetically Modified Chimeric Plasmodium falciparum Parasite Expressing Plasmodium vivax Circumsporozoite Protein for Malaria Vaccine Development
por: Miyazaki, Yukiko, et al.
Publicado: (2020)

The effect of dosage on the protective efficacy of whole-sporozoite formulations for immunization against malaria
por: Moita, Diana, et al.
Publicado: (2023)

Quantification of wild-type and radiation attenuated Plasmodium falciparum sporozoite motility in human skin
por: Winkel, Béatrice M. F., et al.
Publicado: (2019)

Secreted dual reporter assay with Gaussia luciferase and the red fluorescent protein mCherry
por: Wider, Diana, et al.
Publicado: (2017)

Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver
por: Franke-Fayard, Blandine, et al.
Publicado: (2022)

Regulation of Plasmodium sporozoite motility by formulation components
por: de Korne, Clarize M., et al.
Publicado: (2019)

Proteomic Profiling of Plasmodium Sporozoite Maturation Identifies New Proteins Essential for Parasite Development and Infectivity
por: Lasonder, Edwin, et al.
Publicado: (2008)

A Split-Luciferase Reporter Recognizing GFP and mCherry Tags to Facilitate Studies of Protein–Protein Interactions
por: Moustaqil, Mehdi, et al.
Publicado: (2017)

Salivary Gland-Specific P. berghei Reporter Lines Enable Rapid Evaluation of Tissue-Specific Sporozoite Loads in Mosquitoes
por: Ramakrishnan, Chandra, et al.
Publicado: (2012)

Plasmodium sporozoites induce regulatory macrophages
por: Winkel, Béatrice M. F., et al.
Publicado: (2020)

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites
por: van Schaijk, Ben C L, et al.
Publicado: (2014)

Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso
por: Barry, Aissata, et al.
Publicado: (2019)

Protective immunity differs between routes of administration of attenuated malaria parasites independent of parasite liver load
por: Haeberlein, Simone, et al.
Publicado: (2017)

A Novel ‘Gene Insertion/Marker Out’ (GIMO) Method for Transgene Expression and Gene Complementation in Rodent Malaria Parasites
por: Lin, Jing-wen, et al.
Publicado: (2011)

Chemically augmented malaria sporozoites display an altered immunogenic profile
por: Duszenko, Nikolas, et al.
Publicado: (2023)

A conserved U-rich RNA region implicated in regulation of translation in Plasmodium female gametocytes
por: Braks, Joanna A. M., et al.
Publicado: (2008)

Studying the effect of chloroquine on sporozoite-induced protection and immune responses in Plasmodium berghei malaria
por: Bijker, Else M, et al.
Publicado: (2015)

Modelling mosquito infection at natural parasite densities identifies drugs targeting EF2, PI4K or ATP4 as key candidates for interrupting malaria transmission
por: Dechering, Koen J., et al.
Publicado: (2017)

A new P. falciparum gametocyte drug screening assay based on pLDH detection
por: D’Alessandro, Sarah, et al.
Publicado: (2012)

Immunization with genetically attenuated P52-deficient Plasmodium berghei sporozoites induces a long-lasting effector memory CD8(+ )T cell response in the liver
por: Douradinha, Bruno, et al.
Publicado: (2011)

Evaluation of immunity against malaria using luciferase-expressing Plasmodium berghei parasites
por: Ploemen, Ivo, et al.
Publicado: (2011)

Plasmodium berghei sporozoites in nonreplicative vacuole are eliminated by a PI3P‐mediated autophagy‐independent pathway
por: Bindschedler, Annina, et al.
Publicado: (2020)

Clustering and Erratic Movement Patterns of Syringe-Injected versus Mosquito-Inoculated Malaria Sporozoites Underlie Decreased Infectivity
por: de Korne, C. M., et al.
Publicado: (2021)

A semi-automated luminescence based standard membrane feeding assay identifies novel small molecules that inhibit transmission of malaria parasites by mosquitoes
por: Vos, Martijn W., et al.
Publicado: (2015)

Genome-wide RIP-Chip analysis of translational repressor-bound mRNAs in the Plasmodium gametocyte
por: Guerreiro, Ana, et al.
Publicado: (2014)

The Host Protein Aquaporin-9 is Required for Efficient Plasmodium falciparum Sporozoite Entry into Human Hepatocytes
por: Amanzougaghene, Nadia, et al.
Publicado: (2021)

Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites
por: Schats, Remko, et al.
Publicado: (2015)

Plasmodium falciparum gametocyte carriage in asymptomatic children in western Kenya
por: Bousema, J Teun, et al.
Publicado: (2004)

Assessment of the transmission blocking activity of antimalarial compounds by membrane feeding assays using natural Plasmodium falciparum gametocyte isolates from West-Africa
por: B. Henry, Noëlie, et al.
Publicado: (2023)

Submicroscopic Gametocytes and the Transmission of Antifolate-Resistant Plasmodium falciparum in Western Kenya
por: Oesterholt, Mayke J. A. M., et al.
Publicado: (2009)

Flow cytometry for the evaluation of anti-plasmodial activity of drugs on Plasmodium falciparum gametocytes
por: Chevalley, Séverine, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_8rv5idlbodqeijbee6ddvf7k47