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Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling
Enteroendocrine cells (EECs) produce hormones such as glucagon-like peptide 1 and peptide YY that regulate food absorption, insulin secretion, and appetite. Based on the success of glucagon-like peptide 1–based therapies for type 2 diabetes and obesity, EECs are themselves the focus of drug discover...
Autores principales: | Roberts, Geoffrey P., Larraufie, Pierre, Richards, Paul, Kay, Richard G., Galvin, Sam G., Miedzybrodzka, Emily L., Leiter, Andrew, Li, H. Joyce, Glass, Leslie L., Ma, Marcella K.L., Lam, Brian, Yeo, Giles S.H., Scharfmann, Raphaël, Chiarugi, Davide, Hardwick, Richard H., Reimann, Frank, Gribble, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477899/ https://www.ncbi.nlm.nih.gov/pubmed/30733330 http://dx.doi.org/10.2337/db18-0883 |
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