Cargando…

Complement C7 is a novel risk gene for Alzheimer's disease in Han Chinese

Alzheimer's disease is the most common neurodegenerative disease, and has a high level of genetic heritability and population heterogeneity. In this study, we performed the whole-exome sequencing of Han Chinese patients with familial and/or early-onset Alzheimer's disease, followed by inde...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Deng-Feng, Fan, Yu, Xu, Min, Wang, Guihong, Wang, Dong, Li, Jin, Kong, Li-Li, Zhou, Hejiang, Luo, Rongcan, Bi, Rui, Wu, Yong, Li, Guo-Dong, Li, Ming, Luo, Xiong-Jian, Jiang, Hong-Yan, Tan, Liwen, Zhong, Chunjiu, Fang, Yiru, Zhang, Chen, Sheng, Nengyin, Jiang, Tianzi, Yao, Yong-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Biology & Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477931/ https://www.ncbi.nlm.nih.gov/pubmed/31032141 http://dx.doi.org/10.1093/nsr/nwy127

Ejemplares similares

Significance of urine complement proteins in monitoring lupus activity
por: Zhao, Jin, et al.
Publicado: (2022)

A novel missense variant in ACAA1 contributes to early-onset Alzheimer’s disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline
por: Luo, Rongcan, et al.
Publicado: (2021)

Icaritin, an inhibitor of beta-site amyloid cleaving enzyme-1, inhibits secretion of amyloid precursor protein in APP-PS1-HEK293 cells by impeding the amyloidogenic pathway
por: Feng, Fei, et al.
Publicado: (2019)

Effect of icaritin on autophagy-related protein expression in TDP-43-transfected SH-SY5Y cells
por: Zhou, Yanjun, et al.
Publicado: (2022)

Icaritin protects SH-SY5Y cells transfected with TDP-43 by alleviating mitochondrial damage and oxidative stress
por: Zhou, Yongjian, et al.
Publicado: (2021)

Chemical composition, antioxidant and antitumor activities of sub-fractions of wild and cultivated Pleurotus ferulae ethanol extracts
por: Yang, Yi, et al.
Publicado: (2018)

Influenza A virus infects pulmonary microvascular endothelial cells leading to microvascular leakage and release of pro-inflammatory cytokines
por: Han, Tiantian, et al.
Publicado: (2021)

Icaritin attenuates 6-OHDA-induced MN9D cell damage by inhibiting oxidative stress
por: Zhou, Xinyu, et al.
Publicado: (2022)

Serum albumin and albuminuria predict the progression of chronic kidney disease in patients with newly diagnosed type 2 diabetes: a retrospective study
por: Li, Yujiao, et al.
Publicado: (2021)

LncRNA OIP5-AS1 modulates the proliferation and apoptosis of Jurkat cells by sponging miR-181c-5p to regulate IL-7 expression in myasthenia gravis
por: Wang, Xu, et al.
Publicado: (2022)

Targeting B4GALT7 suppresses the proliferation, migration and invasion of hepatocellular carcinoma through the Cdc2/CyclinB1 and miR-338-3p/MMP2 pathway
por: Liu, Chang, et al.
Publicado: (2023)

Abnormal mechanical stress on bicuspid aortic valve induces valvular calcification and inhibits Notch1/NICD/Runx2 signal
por: Li, Guangzhou, et al.
Publicado: (2023)

Knockdown of hsa_circ_0008922 inhibits the progression of glioma
por: Xue, Chunhong, et al.
Publicado: (2022)

Ferroptosis-dependent breast cancer cell-derived exosomes inhibit migration and invasion of breast cancer cells by suppressing M2 macrophage polarization
por: Yi, Chenghao, et al.
Publicado: (2023)

Identification of key genes in sepsis-induced cardiomyopathy based on integrated bioinformatical analysis and experiments in vitro and in vivo
por: Liu, Dehua, et al.
Publicado: (2023)

Glucosylceramide synthase regulates hepatocyte repair after concanavalin A-induced immune-mediated liver injury
por: Gan, Jian, et al.
Publicado: (2021)

Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction
por: Luo, Chao, et al.
Publicado: (2021)

Ac2-26 attenuates hepatic ischemia-reperfusion injury in mice via regulating IL-22/IL-22R1/STAT3 signaling
por: Li, Wanzhen, et al.
Publicado: (2022)

Immune function of miR-214 and its application prospects as molecular marker
por: Wang, Qiuyuan, et al.
Publicado: (2021)

Progress in the mechanism of autophagy and traditional Chinese medicine herb involved in alcohol-related liver disease
por: Han, Wenwen, et al.
Publicado: (2023)

Comparative studies of two AA10 family lytic polysaccharide monooxygenases from Bacillus thuringiensis
por: Zhang, Huiyan, et al.
Publicado: (2023)

Deciphering pathological behavior of pediatric medullary thyroid cancer from single-cell perspective
por: Chen, De-qian, et al.
Publicado: (2023)

Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3
por: Osicka, Radim, et al.
Publicado: (2015)

lncRNA H19 is involved in TGF-β1-induced epithelial to mesenchymal transition in bovine epithelial cells through PI3K/AKT Signaling Pathway
por: Yang, Wei, et al.
Publicado: (2017)

Identification of species and materia medica within Saussurea subg. Amphilaena based on DNA barcodes
por: Chen, Jie, et al.
Publicado: (2019)

N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats
por: Pan, Yitong, et al.
Publicado: (2021)

A comprehensive review of circRNA: from purification and identification to disease marker potential
por: Xu, Sheng, et al.
Publicado: (2018)

Identification of two short peptide motifs from serine/arginine-rich protein ribonucleic acid recognition motif-1 domain acting as splicing regulators
por: Jiang, Tao, et al.
Publicado: (2023)

Involvement of TOB1 on autophagy in gastric cancer AGS cells via decreasing the activation of AKT/mTOR signaling pathway
por: Wang, Dong, et al.
Publicado: (2022)

Raptor couples mTORC1 and ERK1/2 inhibition by cardamonin with oxidative stress induction in ovarian cancer cells
por: Zhu, Yanting, et al.
Publicado: (2023)

Analysis of influencing factors of serum total protein and serum calcium content in plasma donors
por: Liu, Bin, et al.
Publicado: (2022)

Influences of ABO blood group, age and gender on plasma coagulation factor VIII, fibrinogen, von Willebrand factor and ADAMTS13 levels in a Chinese population
por: Wang, Zongkui, et al.
Publicado: (2017)

Recombinant fusion protein by lysozyme and antibacterial peptide enhances ischemic wound healing via angiogenesis and reduction of inflammation in diabetic db/db mice
por: Li, Wei, et al.
Publicado: (2021)

Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization
por: Liu, Zhong-Yu, et al.
Publicado: (2016)

Prognostic value of high-sensitivity cardiac troponin for major adverse cardiovascular events in patients with diabetes: a systematic review and meta-analysis
por: Song, Tiange, et al.
Publicado: (2023)

GDF11 induces differentiation and apoptosis and inhibits migration of C17.2 neural stem cells via modulating MAPK signaling pathway
por: Wang, Zongkui, et al.
Publicado: (2018)

The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlying locust phase transition
por: Hou, Li, et al.
Publicado: (2017)

Design of new acid-activated cell-penetrating peptides for tumor drug delivery
por: Yao, Jia, et al.
Publicado: (2017)

Effect of mesoporous bioactive glass on odontogenic differentiation of human dental pulp stem cells
por: Zhu, Lin, et al.
Publicado: (2021)

Comparative transcriptomic analyses of chlorogenic acid and luteolosides biosynthesis pathways at different flowering stages of diploid and tetraploid Lonicera japonica
por: Wang, Hongli, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_3vg1489jhkbrijea4693albdmm