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Feasibility of bisphosphonate therapy in an Indian pediatric patient of fibrodysplasia ossificans progressiva

Fibrodysplasia ossificans progressiva, also known as myositis ossificans progressiva, is a rare autosomal dominant disorder (1 in 2 million). It produces a catastrophic and crippling illness in young people for which there is no effective treatment. This case report presents a case of 7-year-old chi...

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Detalles Bibliográficos
Autores principales: Kochar, Inderpal Singh, Sethi, Aashish, Ramachandran, Smita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477960/
https://www.ncbi.nlm.nih.gov/pubmed/31041177
http://dx.doi.org/10.4103/ijabmr.IJABMR_52_18
Descripción
Sumario:Fibrodysplasia ossificans progressiva, also known as myositis ossificans progressiva, is a rare autosomal dominant disorder (1 in 2 million). It produces a catastrophic and crippling illness in young people for which there is no effective treatment. This case report presents a case of 7-year-old child misdiagnosed as osteogenesis imperfecta admitted with severe disability and pain. He was diagnosed by clinical and radiological methods, treated with bisphosphonates for pain relief along with calcium and Vitamin D, and followed till 4 years.