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Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages

OBJECTIVES: ESBL-producing Klebsiella pneumoniae (KPN) pose a major threat to human health globally. We carried out a WGS study to understand the genetic background of ESBL-producing KPN in Malawi and place them in the context of other global isolates. METHODS: We sequenced genomes of 72 invasive an...

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Detalles Bibliográficos
Autores principales: Musicha, Patrick, Msefula, Chisomo L, Mather, Alison E, Chaguza, Chrispin, Cain, Amy K, Peno, Chikondi, Kallonen, Teemu, Khonga, Margaret, Denis, Brigitte, Gray, Katherine J, Heyderman, Robert S, Thomson, Nicholas R, Everett, Dean B, Feasey, Nicholas A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477993/
https://www.ncbi.nlm.nih.gov/pubmed/30778540
http://dx.doi.org/10.1093/jac/dkz032