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Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo
How action potentials regulate myelination by oligodendrocytes is uncertain. We show that neuronal activity raises [Ca(2+)](i) in developing oligodendrocytes in vivo, and that myelin sheath elongation is promoted by a high frequency of [Ca(2+)](i) transients and prevented by [Ca(2+)](i)-buffering. S...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478117/ https://www.ncbi.nlm.nih.gov/pubmed/29230052 http://dx.doi.org/10.1038/s41593-017-0031-y |