Novel Picornavirus in Lambs with Severe Encephalomyelitis

Using metagenomic analysis, we identified a novel picornavirus in young preweaned lambs with neurologic signs associated with severe nonsuppurative encephalitis and sensory ganglionitis in 2016 and 2017 in the United Kingdom. In situ hybridization demonstrated intralesional neuronotropism of this vi...

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Autores principales: Forth, Leonie F., Scholes, Sandra F.E., Pesavento, Patricia A., Jackson, Kenneth, Mackintosh, Adrienne, Carson, Amanda, Howie, Fiona, Schlottau, Kore, Wernike, Kerstin, Pohlmann, Anne, Höper, Dirk, Beer, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478204/
https://www.ncbi.nlm.nih.gov/pubmed/31002069
http://dx.doi.org/10.3201/eid2505.181573
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author Forth, Leonie F.
Scholes, Sandra F.E.
Pesavento, Patricia A.
Jackson, Kenneth
Mackintosh, Adrienne
Carson, Amanda
Howie, Fiona
Schlottau, Kore
Wernike, Kerstin
Pohlmann, Anne
Höper, Dirk
Beer, Martin
author_facet Forth, Leonie F.
Scholes, Sandra F.E.
Pesavento, Patricia A.
Jackson, Kenneth
Mackintosh, Adrienne
Carson, Amanda
Howie, Fiona
Schlottau, Kore
Wernike, Kerstin
Pohlmann, Anne
Höper, Dirk
Beer, Martin
author_sort Forth, Leonie F.
collection PubMed
description Using metagenomic analysis, we identified a novel picornavirus in young preweaned lambs with neurologic signs associated with severe nonsuppurative encephalitis and sensory ganglionitis in 2016 and 2017 in the United Kingdom. In situ hybridization demonstrated intralesional neuronotropism of this virus, which was also detected in archived samples of similarly affected lambs (1998–2014).
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spelling pubmed-64782042019-05-08 Novel Picornavirus in Lambs with Severe Encephalomyelitis Forth, Leonie F. Scholes, Sandra F.E. Pesavento, Patricia A. Jackson, Kenneth Mackintosh, Adrienne Carson, Amanda Howie, Fiona Schlottau, Kore Wernike, Kerstin Pohlmann, Anne Höper, Dirk Beer, Martin Emerg Infect Dis Dispatch Using metagenomic analysis, we identified a novel picornavirus in young preweaned lambs with neurologic signs associated with severe nonsuppurative encephalitis and sensory ganglionitis in 2016 and 2017 in the United Kingdom. In situ hybridization demonstrated intralesional neuronotropism of this virus, which was also detected in archived samples of similarly affected lambs (1998–2014). Centers for Disease Control and Prevention 2019-05 /pmc/articles/PMC6478204/ /pubmed/31002069 http://dx.doi.org/10.3201/eid2505.181573 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Forth, Leonie F.
Scholes, Sandra F.E.
Pesavento, Patricia A.
Jackson, Kenneth
Mackintosh, Adrienne
Carson, Amanda
Howie, Fiona
Schlottau, Kore
Wernike, Kerstin
Pohlmann, Anne
Höper, Dirk
Beer, Martin
Novel Picornavirus in Lambs with Severe Encephalomyelitis
title Novel Picornavirus in Lambs with Severe Encephalomyelitis
title_full Novel Picornavirus in Lambs with Severe Encephalomyelitis
title_fullStr Novel Picornavirus in Lambs with Severe Encephalomyelitis
title_full_unstemmed Novel Picornavirus in Lambs with Severe Encephalomyelitis
title_short Novel Picornavirus in Lambs with Severe Encephalomyelitis
title_sort novel picornavirus in lambs with severe encephalomyelitis
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478204/
https://www.ncbi.nlm.nih.gov/pubmed/31002069
http://dx.doi.org/10.3201/eid2505.181573
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