Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France

We prospectively examined the effectiveness of diagnostic tests for anaplasmosis using patients with suspected diagnoses in France. PCR (sensitivity 0.74, specificity 1) was the best-suited test. Serology had a lower specificity but higher sensitivity when testing acute and convalescent samples. PCR...

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Autores principales: Hansmann, Yves, Jaulhac, Benoit, Kieffer, Pierre, Martinot, Martin, Wurtz, Elisabeth, Dukic, Régis, Boess, Geneviève, Michel, André, Strady, Christophe, Sagez, Jean François, Lefebvre, Nicolas, Talagrand-Reboul, Emilie, Argemi, Xavier, De Martino, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478229/
https://www.ncbi.nlm.nih.gov/pubmed/31002073
http://dx.doi.org/10.3201/eid2505.171751
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author Hansmann, Yves
Jaulhac, Benoit
Kieffer, Pierre
Martinot, Martin
Wurtz, Elisabeth
Dukic, Régis
Boess, Geneviève
Michel, André
Strady, Christophe
Sagez, Jean François
Lefebvre, Nicolas
Talagrand-Reboul, Emilie
Argemi, Xavier
De Martino, Sylvie
author_facet Hansmann, Yves
Jaulhac, Benoit
Kieffer, Pierre
Martinot, Martin
Wurtz, Elisabeth
Dukic, Régis
Boess, Geneviève
Michel, André
Strady, Christophe
Sagez, Jean François
Lefebvre, Nicolas
Talagrand-Reboul, Emilie
Argemi, Xavier
De Martino, Sylvie
author_sort Hansmann, Yves
collection PubMed
description We prospectively examined the effectiveness of diagnostic tests for anaplasmosis using patients with suspected diagnoses in France. PCR (sensitivity 0.74, specificity 1) was the best-suited test. Serology had a lower specificity but higher sensitivity when testing acute and convalescent samples. PCR and serology should be used in combination for anaplasmosis diagnosis.
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spelling pubmed-64782292019-05-08 Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France Hansmann, Yves Jaulhac, Benoit Kieffer, Pierre Martinot, Martin Wurtz, Elisabeth Dukic, Régis Boess, Geneviève Michel, André Strady, Christophe Sagez, Jean François Lefebvre, Nicolas Talagrand-Reboul, Emilie Argemi, Xavier De Martino, Sylvie Emerg Infect Dis Dispatch We prospectively examined the effectiveness of diagnostic tests for anaplasmosis using patients with suspected diagnoses in France. PCR (sensitivity 0.74, specificity 1) was the best-suited test. Serology had a lower specificity but higher sensitivity when testing acute and convalescent samples. PCR and serology should be used in combination for anaplasmosis diagnosis. Centers for Disease Control and Prevention 2019-05 /pmc/articles/PMC6478229/ /pubmed/31002073 http://dx.doi.org/10.3201/eid2505.171751 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Hansmann, Yves
Jaulhac, Benoit
Kieffer, Pierre
Martinot, Martin
Wurtz, Elisabeth
Dukic, Régis
Boess, Geneviève
Michel, André
Strady, Christophe
Sagez, Jean François
Lefebvre, Nicolas
Talagrand-Reboul, Emilie
Argemi, Xavier
De Martino, Sylvie
Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France
title Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France
title_full Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France
title_fullStr Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France
title_full_unstemmed Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France
title_short Value of PCR, Serology, and Blood Smears for Human Granulocytic Anaplasmosis Diagnosis, France
title_sort value of pcr, serology, and blood smears for human granulocytic anaplasmosis diagnosis, france
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478229/
https://www.ncbi.nlm.nih.gov/pubmed/31002073
http://dx.doi.org/10.3201/eid2505.171751
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