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How can memories last for days, years, or a lifetime? Proposed mechanisms for maintaining synaptic potentiation and memory

With memory encoding reliant on persistent changes in the properties of synapses, a key question is how can memories be maintained from days to months or a lifetime given molecular turnover? It is likely that positive feedback loops are necessary to persistently maintain the strength of synapses tha...

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Detalles Bibliográficos
Autores principales: Smolen, Paul, Baxter, Douglas A., Byrne, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478248/
https://www.ncbi.nlm.nih.gov/pubmed/30992383
http://dx.doi.org/10.1101/lm.049395.119