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Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth

The best measure to limit spread of contagious diseases caused by influenza A viruses (IAVs) is annual vaccination. The growing global demand for low-cost vaccines requires the establishment of high-yield production processes. One possible option to address this challenge is the engineering of novel...

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Detalles Bibliográficos
Autores principales:	Laske, Tanja, Bachmann, Mandy, Dostert, Melanie, Karlas, Alexander, Wirth, Dagmar, Frensing, Timo, Meyer, Thomas F., Hauser, Hansjörg, Reichl, Udo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478349/ https://www.ncbi.nlm.nih.gov/pubmed/30973879 http://dx.doi.org/10.1371/journal.pcbi.1006944

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