Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics

Acyl CoA metabolites derived from the catabolism of carbon fuels can react with lysine residues of mitochondrial proteins, giving rise to a large family of post-translational modifications (PTMs). Mass spectrometry-based detection of thousands of acyl-PTMs scattered throughout the proteome has estab...

Descripción completa

Detalles Bibliográficos
Autores principales: Fisher-Wellman, Kelsey H., Draper, James A., Davidson, Michael T., Williams, Ashley S., Narowski, Tara M., Slentz, Dorothy H., Ilkayeva, Olga R., Stevens, Robert D., Wagner, Gregory R., Najjar, Rami, Hirschey, Mathew D., Thompson, J. Will, Olson, David P., Kelly, Daniel P., Koves, Timothy R., Grimsrud, Paul A., Muoio, Deborah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478502/
https://www.ncbi.nlm.nih.gov/pubmed/30726738
http://dx.doi.org/10.1016/j.celrep.2019.01.057

Ejemplares similares

Ejemplares similares