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Simultaneous Determination of Selegiline, Desmethylselegiline, R/S-methamphetamine, and R/S-amphetamine on Dried Urine Spots by LC/MS/MS: Application to a Pharmacokinetic Study in Urine

Objective: Chiral analysis is a crucial method to differentiate selegiline intake from drug abuse. A dried urine spot (DUS) analytical method based on spotting urine samples (10 μL) onto dried spot collection cards, and followed by air-drying and extraction, was developed and validated for the deter...

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Detalles Bibliográficos
Autores principales: Chen, Lizhu, Yu, Yingjia, Duan, Gengli, Wang, Xin, Shen, Baohua, Xiang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478707/
https://www.ncbi.nlm.nih.gov/pubmed/31058136
http://dx.doi.org/10.3389/fchem.2019.00248

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