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Simultaneous Determination of Selegiline, Desmethylselegiline, R/S-methamphetamine, and R/S-amphetamine on Dried Urine Spots by LC/MS/MS: Application to a Pharmacokinetic Study in Urine
Objective: Chiral analysis is a crucial method to differentiate selegiline intake from drug abuse. A dried urine spot (DUS) analytical method based on spotting urine samples (10 μL) onto dried spot collection cards, and followed by air-drying and extraction, was developed and validated for the deter...
Autores principales: | Chen, Lizhu, Yu, Yingjia, Duan, Gengli, Wang, Xin, Shen, Baohua, Xiang, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478707/ https://www.ncbi.nlm.nih.gov/pubmed/31058136 http://dx.doi.org/10.3389/fchem.2019.00248 |
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