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An inner activation gate controls TMEM16F phospholipid scrambling
Transmembrane protein 16F (TMEM16F) is an enigmatic Ca(2+)-activated phospholipid scramblase (CaPLSase) that passively transports phospholipids down their chemical gradients and mediates blood coagulation, bone development and viral infection. Despite recent advances in the structure and function un...
Autores principales: | Le, Trieu, Jia, Zhiguang, Le, Son C., Zhang, Yang, Chen, Jianhan, Yang, Huanghe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478717/ https://www.ncbi.nlm.nih.gov/pubmed/31015464 http://dx.doi.org/10.1038/s41467-019-09778-7 |
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