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SIRT3 mediates hippocampal synaptic adaptations to intermittent fasting and ameliorates deficits in APP mutant mice

Intermittent food deprivation (fasting, IF) improves mood and cognition and protects neurons against excitotoxic degeneration in animal models of epilepsy and Alzheimer’s disease (AD). The mechanisms by which neuronal networks adapt to IF and how such adaptations impact neuropathological processes a...

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Detalles Bibliográficos
Autores principales:	Liu, Yong, Cheng, Aiwu, Li, Yu-Jiao, Yang, Ying, Kishimoto, Yuki, Zhang, Shi, Wang, Yue, Wan, Ruiqian, Raefsky, Sophia M., Lu, Daoyuan, Saito, Takashi, Saido, Takaomi, Zhu, Jian, Wu, Long-Jun, Mattson, Mark P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478744/ https://www.ncbi.nlm.nih.gov/pubmed/31015456 http://dx.doi.org/10.1038/s41467-019-09897-1

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