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Biomedical applications of polyelectrolyte coated spherical gold nanoparticles
Surface modified gold nanoparticles are becoming more and more popular for use in biomaterials due to the possibility for specific targeting and increased biocompatibility. This review provides a summary of the recent literature surrounding polyelectrolyte coatings on spherical gold nanoparticles an...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478786/ https://www.ncbi.nlm.nih.gov/pubmed/31016413 http://dx.doi.org/10.1186/s40580-019-0183-4 |
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author | Fuller, Melanie A. Köper, Ingo |
author_facet | Fuller, Melanie A. Köper, Ingo |
author_sort | Fuller, Melanie A. |
collection | PubMed |
description | Surface modified gold nanoparticles are becoming more and more popular for use in biomaterials due to the possibility for specific targeting and increased biocompatibility. This review provides a summary of the recent literature surrounding polyelectrolyte coatings on spherical gold nanoparticles and their potential biomedical applications. The synthesis and layer-by layer coating approach are briefly discussed together with common characterisation methods. The potential applications and recent developments in drug delivery, gene therapy, photothermal therapy and imaging are summarized as well as the effects on cellular uptake and toxicity. Finally, the future outlook for polyelectrolyte coated gold nanoparticles is explored, focusing on their use in biomedicine. [Image: see text] |
format | Online Article Text |
id | pubmed-6478786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer Singapore |
record_format | MEDLINE/PubMed |
spelling | pubmed-64787862019-05-15 Biomedical applications of polyelectrolyte coated spherical gold nanoparticles Fuller, Melanie A. Köper, Ingo Nano Converg Review Surface modified gold nanoparticles are becoming more and more popular for use in biomaterials due to the possibility for specific targeting and increased biocompatibility. This review provides a summary of the recent literature surrounding polyelectrolyte coatings on spherical gold nanoparticles and their potential biomedical applications. The synthesis and layer-by layer coating approach are briefly discussed together with common characterisation methods. The potential applications and recent developments in drug delivery, gene therapy, photothermal therapy and imaging are summarized as well as the effects on cellular uptake and toxicity. Finally, the future outlook for polyelectrolyte coated gold nanoparticles is explored, focusing on their use in biomedicine. [Image: see text] Springer Singapore 2019-04-24 /pmc/articles/PMC6478786/ /pubmed/31016413 http://dx.doi.org/10.1186/s40580-019-0183-4 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Review Fuller, Melanie A. Köper, Ingo Biomedical applications of polyelectrolyte coated spherical gold nanoparticles |
title | Biomedical applications of polyelectrolyte coated spherical gold nanoparticles |
title_full | Biomedical applications of polyelectrolyte coated spherical gold nanoparticles |
title_fullStr | Biomedical applications of polyelectrolyte coated spherical gold nanoparticles |
title_full_unstemmed | Biomedical applications of polyelectrolyte coated spherical gold nanoparticles |
title_short | Biomedical applications of polyelectrolyte coated spherical gold nanoparticles |
title_sort | biomedical applications of polyelectrolyte coated spherical gold nanoparticles |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478786/ https://www.ncbi.nlm.nih.gov/pubmed/31016413 http://dx.doi.org/10.1186/s40580-019-0183-4 |
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