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Targeting T Cell Activation and Lupus Autoimmune Phenotypes by Inhibiting Glucose Transporters
CD4(+) T cells have numerous features of over-activated cellular metabolism in lupus patients and mouse models of the disease. This includes a higher glycolysis than in healthy controls. Glucose transporters play an essential role in glucose metabolism by controlling glucose import into the cell fro...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478810/ https://www.ncbi.nlm.nih.gov/pubmed/31057554 http://dx.doi.org/10.3389/fimmu.2019.00833 |