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Iron deficiency disrupts embryonic haematopoiesis but not the endothelial to haematopoietic transition
In this study, we aimed to explore how cellular iron status affects embryonic haematopoiesis. For this purpose, we used a model of mouse embryonic stem cell differentiation into embryonic haematopoietic progenitors. We modulated the iron status by adding either the iron chelator Deferoxamine (DFO) f...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478831/ https://www.ncbi.nlm.nih.gov/pubmed/31015568 http://dx.doi.org/10.1038/s41598-019-42765-y |