Cargando…
A survival selection strategy for engineering synthetic binding proteins that specifically recognize post-translationally phosphorylated proteins
There is an urgent need for affinity reagents that target phospho-modified sites on individual proteins; however, generating such reagents remains a significant challenge. Here, we describe a genetic selection strategy for routine laboratory isolation of phospho-specific designed ankyrin repeat prot...
| Autores principales: | , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478843/ https://www.ncbi.nlm.nih.gov/pubmed/31015433 http://dx.doi.org/10.1038/s41467-019-09854-y |