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Mechanistic modelling supports entwined rather than exclusively competitive DNA double-strand break repair pathway

Following radiation induced DNA damage, several repair pathways are activated to help preserve genome integrity. Double Strand Breaks (DSBs), which are highly toxic, have specified repair pathways to address them. The main repair pathways used to resolve DSBs are Non-Homologous End Joining (NHEJ) an...

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Detalles Bibliográficos
Autores principales:	Ingram, S. P., Warmenhoven, J. W., Henthorn, N. T., Smith, E. A. K., Chadwick, A. L., Burnet, N. G., Mackay, R. I., Kirkby, N. F., Kirkby, K. J., Merchant, M. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478946/ https://www.ncbi.nlm.nih.gov/pubmed/31015540 http://dx.doi.org/10.1038/s41598-019-42901-8

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