Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis

The patient was a 71-year-old man with severe idiopathic pulmonary fibrosis (IPF) and who demonstrated a slow deterioration of his respiratory condition. After nintedanib administration, his forced vital capacity and chest high-resolution computed tomography (HRCT) findings were stable, but his dysp...

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Autores principales: Shimomura, Iwao, Abe, Mitsuhiro, Li, Yu, Tsushima, Kenji, Sakao, Seiichiro, Tanabe, Nobuhiro, Ikusaka, Masatomi, Tatsumi, Koichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478987/
https://www.ncbi.nlm.nih.gov/pubmed/30568123
http://dx.doi.org/10.2169/internalmedicine.1384-18
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author Shimomura, Iwao
Abe, Mitsuhiro
Li, Yu
Tsushima, Kenji
Sakao, Seiichiro
Tanabe, Nobuhiro
Ikusaka, Masatomi
Tatsumi, Koichiro
author_facet Shimomura, Iwao
Abe, Mitsuhiro
Li, Yu
Tsushima, Kenji
Sakao, Seiichiro
Tanabe, Nobuhiro
Ikusaka, Masatomi
Tatsumi, Koichiro
author_sort Shimomura, Iwao
collection PubMed
description The patient was a 71-year-old man with severe idiopathic pulmonary fibrosis (IPF) and who demonstrated a slow deterioration of his respiratory condition. After nintedanib administration, his forced vital capacity and chest high-resolution computed tomography (HRCT) findings were stable, but his dyspnea on exertion were worsened. He was diagnosed with pulmonary hypertension (PH) by right heart catheterization (mean pulmonary arterial pressure: 30 mmHg). In this case, we suspected that nintedanib caused his PH, as his IPF had not progressed.
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spelling pubmed-64789872019-04-24 Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis Shimomura, Iwao Abe, Mitsuhiro Li, Yu Tsushima, Kenji Sakao, Seiichiro Tanabe, Nobuhiro Ikusaka, Masatomi Tatsumi, Koichiro Intern Med Case Report The patient was a 71-year-old man with severe idiopathic pulmonary fibrosis (IPF) and who demonstrated a slow deterioration of his respiratory condition. After nintedanib administration, his forced vital capacity and chest high-resolution computed tomography (HRCT) findings were stable, but his dyspnea on exertion were worsened. He was diagnosed with pulmonary hypertension (PH) by right heart catheterization (mean pulmonary arterial pressure: 30 mmHg). In this case, we suspected that nintedanib caused his PH, as his IPF had not progressed. The Japanese Society of Internal Medicine 2018-12-18 2019-04-01 /pmc/articles/PMC6478987/ /pubmed/30568123 http://dx.doi.org/10.2169/internalmedicine.1384-18 Text en Copyright © 2019 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Shimomura, Iwao
Abe, Mitsuhiro
Li, Yu
Tsushima, Kenji
Sakao, Seiichiro
Tanabe, Nobuhiro
Ikusaka, Masatomi
Tatsumi, Koichiro
Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis
title Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis
title_full Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis
title_fullStr Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis
title_full_unstemmed Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis
title_short Pulmonary Hypertension Exacerbated by Nintedanib Administration for Idiopathic Pulmonary Fibrosis
title_sort pulmonary hypertension exacerbated by nintedanib administration for idiopathic pulmonary fibrosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478987/
https://www.ncbi.nlm.nih.gov/pubmed/30568123
http://dx.doi.org/10.2169/internalmedicine.1384-18
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