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Metabolic Syndrome and Male Fertility
Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Sexual Medicine and Andrology
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479081/ https://www.ncbi.nlm.nih.gov/pubmed/30350486 http://dx.doi.org/10.5534/wjmh.180055 |
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author | Martins, Ana Dias Majzoub, Ahmad Agawal, Ashok |
author_facet | Martins, Ana Dias Majzoub, Ahmad Agawal, Ashok |
author_sort | Martins, Ana Dias |
collection | PubMed |
description | Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through studying the relationship between MetS and male reproductive health. The effects of obesity, dyslipidemia, hypertension, and insulin resistance on male fertility were examined and supporting evidence explaining the pathophysiology of sperm dysfunction with each MetS component were described. Adopting a healthy lifestyle appears to be the single most important intervention to prevent the unwanted effects of MetS on men's health and fertility. Further studies addressing the components of MetS and their impact on male reproduction are required to enhance our understanding of the underlying pathophysiology and to propose new methods for therapeutic intervention. |
format | Online Article Text |
id | pubmed-6479081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Korean Society for Sexual Medicine and Andrology |
record_format | MEDLINE/PubMed |
spelling | pubmed-64790812019-05-08 Metabolic Syndrome and Male Fertility Martins, Ana Dias Majzoub, Ahmad Agawal, Ashok World J Mens Health Review Article Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through studying the relationship between MetS and male reproductive health. The effects of obesity, dyslipidemia, hypertension, and insulin resistance on male fertility were examined and supporting evidence explaining the pathophysiology of sperm dysfunction with each MetS component were described. Adopting a healthy lifestyle appears to be the single most important intervention to prevent the unwanted effects of MetS on men's health and fertility. Further studies addressing the components of MetS and their impact on male reproduction are required to enhance our understanding of the underlying pathophysiology and to propose new methods for therapeutic intervention. Korean Society for Sexual Medicine and Andrology 2019-05 2018-10-22 /pmc/articles/PMC6479081/ /pubmed/30350486 http://dx.doi.org/10.5534/wjmh.180055 Text en Copyright © 2019 Korean Society for Sexual Medicine and Andrology http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Martins, Ana Dias Majzoub, Ahmad Agawal, Ashok Metabolic Syndrome and Male Fertility |
title | Metabolic Syndrome and Male Fertility |
title_full | Metabolic Syndrome and Male Fertility |
title_fullStr | Metabolic Syndrome and Male Fertility |
title_full_unstemmed | Metabolic Syndrome and Male Fertility |
title_short | Metabolic Syndrome and Male Fertility |
title_sort | metabolic syndrome and male fertility |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479081/ https://www.ncbi.nlm.nih.gov/pubmed/30350486 http://dx.doi.org/10.5534/wjmh.180055 |
work_keys_str_mv | AT martinsanadias metabolicsyndromeandmalefertility AT majzoubahmad metabolicsyndromeandmalefertility AT agawalashok metabolicsyndromeandmalefertility |