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Functional and pharmacological characterization of an S5 domain hERG mutation associated with short QT syndrome
Congenital short QT syndrome (SQTS) is a repolarization disorder characterized by abbreviated QT intervals, atrial and ventricular arrhythmias and a risk of sudden death. This study characterized a missense mutation (I560T) in the S5 domain of the hERG K(+) channel that has been associated with vari...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479114/ https://www.ncbi.nlm.nih.gov/pubmed/31049424 http://dx.doi.org/10.1016/j.heliyon.2019.e01429 |