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A very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis

Scrofuloderma is a clinical form of secondary cutaneous tuberculosis. It is commonly characterized by bluish-red nodules that cover the lymph nodes, bones or joints, disrupting the affected tissue to be replaced with granulation tissue. We reported a case of 10-year-old boy with ulcers in the cervic...

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Autores principales: Soeroso, Noni Novisari, Harina, Endah Galih, Yosi, Aryati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479154/
https://www.ncbi.nlm.nih.gov/pubmed/31049283
http://dx.doi.org/10.1016/j.rmcr.2019.100842
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author Soeroso, Noni Novisari
Harina, Endah Galih
Yosi, Aryati
author_facet Soeroso, Noni Novisari
Harina, Endah Galih
Yosi, Aryati
author_sort Soeroso, Noni Novisari
collection PubMed
description Scrofuloderma is a clinical form of secondary cutaneous tuberculosis. It is commonly characterized by bluish-red nodules that cover the lymph nodes, bones or joints, disrupting the affected tissue to be replaced with granulation tissue. We reported a case of 10-year-old boy with ulcers in the cervical and axillary region. The lesion began as papules, which gradually developed into nodules and pustules. Chronic cough was also found, however chest x ray was normal and sputum direct smear for acid fast bacil was negative. Histopathologic finding of tissue biopsy revealed epidermal necrosis in the central part surrounded by granulomatous tissue forming an abscess and histiocyte infiltrates, confirming the diagnosis of scrofuloderma. CT Scan of neck showed multiple enlarged lymph nodes, and FNAB result was suggestive for tuberculous lymphadenitis. Patient was then given anti-tuberculosis therapy. Four months later, the ulcers began to resolve and heal gradually.
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spelling pubmed-64791542019-05-02 A very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis Soeroso, Noni Novisari Harina, Endah Galih Yosi, Aryati Respir Med Case Rep Article Scrofuloderma is a clinical form of secondary cutaneous tuberculosis. It is commonly characterized by bluish-red nodules that cover the lymph nodes, bones or joints, disrupting the affected tissue to be replaced with granulation tissue. We reported a case of 10-year-old boy with ulcers in the cervical and axillary region. The lesion began as papules, which gradually developed into nodules and pustules. Chronic cough was also found, however chest x ray was normal and sputum direct smear for acid fast bacil was negative. Histopathologic finding of tissue biopsy revealed epidermal necrosis in the central part surrounded by granulomatous tissue forming an abscess and histiocyte infiltrates, confirming the diagnosis of scrofuloderma. CT Scan of neck showed multiple enlarged lymph nodes, and FNAB result was suggestive for tuberculous lymphadenitis. Patient was then given anti-tuberculosis therapy. Four months later, the ulcers began to resolve and heal gradually. Elsevier 2019-04-17 /pmc/articles/PMC6479154/ /pubmed/31049283 http://dx.doi.org/10.1016/j.rmcr.2019.100842 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Soeroso, Noni Novisari
Harina, Endah Galih
Yosi, Aryati
A very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis
title A very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis
title_full A very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis
title_fullStr A very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis
title_full_unstemmed A very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis
title_short A very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis
title_sort very rare case of scrofuloderma with multiple cervical lymphadenitis tuberculosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479154/
https://www.ncbi.nlm.nih.gov/pubmed/31049283
http://dx.doi.org/10.1016/j.rmcr.2019.100842
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