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Tuberculosis in children presenting with chylothorax - Report of two cases and review of the literature

One third of the world's population is estimated to be infected with Mycobacterium tuberculosis. Tuberculosis (TB) is endemic in many sub-Saharan African counties. The burden is further made worse by the HIV scourge. The number of children with TB and its attendant complications, is equally on...

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Autores principales: Ayuk, Adaeze Chikaodinaka, Gray, Diane, Vanker, Aneesa, Zampoli, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479155/
https://www.ncbi.nlm.nih.gov/pubmed/31049284
http://dx.doi.org/10.1016/j.rmcr.2019.100848
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author Ayuk, Adaeze Chikaodinaka
Gray, Diane
Vanker, Aneesa
Zampoli, Marco
author_facet Ayuk, Adaeze Chikaodinaka
Gray, Diane
Vanker, Aneesa
Zampoli, Marco
author_sort Ayuk, Adaeze Chikaodinaka
collection PubMed
description One third of the world's population is estimated to be infected with Mycobacterium tuberculosis. Tuberculosis (TB) is endemic in many sub-Saharan African counties. The burden is further made worse by the HIV scourge. The number of children with TB and its attendant complications, is equally on the rise. TB can mimic many diseases ranging from infections to malignancies. Among pleuro-pulmonary TB complications, exudative effusion is more common while chylothorax is rare and thus easily missed especially if not the classical milky appearance. We present two children from a TB endemic region, with microbiologically-confirmed TB presenting with chylothoraces that were initially misdiagnosed as pleural empyema. Tuberculosis in children presenting as chylothorax is uncommon. These cases are instructive as they bring to the fore the importance of a full investigation of pleural effusions in children, to ensure a correct diagnosis and prompt effective management.
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spelling pubmed-64791552019-05-02 Tuberculosis in children presenting with chylothorax - Report of two cases and review of the literature Ayuk, Adaeze Chikaodinaka Gray, Diane Vanker, Aneesa Zampoli, Marco Respir Med Case Rep Article One third of the world's population is estimated to be infected with Mycobacterium tuberculosis. Tuberculosis (TB) is endemic in many sub-Saharan African counties. The burden is further made worse by the HIV scourge. The number of children with TB and its attendant complications, is equally on the rise. TB can mimic many diseases ranging from infections to malignancies. Among pleuro-pulmonary TB complications, exudative effusion is more common while chylothorax is rare and thus easily missed especially if not the classical milky appearance. We present two children from a TB endemic region, with microbiologically-confirmed TB presenting with chylothoraces that were initially misdiagnosed as pleural empyema. Tuberculosis in children presenting as chylothorax is uncommon. These cases are instructive as they bring to the fore the importance of a full investigation of pleural effusions in children, to ensure a correct diagnosis and prompt effective management. Elsevier 2019-04-17 /pmc/articles/PMC6479155/ /pubmed/31049284 http://dx.doi.org/10.1016/j.rmcr.2019.100848 Text en © 2019 The Authors. Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Ayuk, Adaeze Chikaodinaka
Gray, Diane
Vanker, Aneesa
Zampoli, Marco
Tuberculosis in children presenting with chylothorax - Report of two cases and review of the literature
title Tuberculosis in children presenting with chylothorax - Report of two cases and review of the literature
title_full Tuberculosis in children presenting with chylothorax - Report of two cases and review of the literature
title_fullStr Tuberculosis in children presenting with chylothorax - Report of two cases and review of the literature
title_full_unstemmed Tuberculosis in children presenting with chylothorax - Report of two cases and review of the literature
title_short Tuberculosis in children presenting with chylothorax - Report of two cases and review of the literature
title_sort tuberculosis in children presenting with chylothorax - report of two cases and review of the literature
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479155/
https://www.ncbi.nlm.nih.gov/pubmed/31049284
http://dx.doi.org/10.1016/j.rmcr.2019.100848
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