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A benign process for the recovery of solanesol from tomato leaf waste
Solanesol, the precursor for the synthesis of coenzyme Q10, is currently recovered from tobacco leaves by conventional extraction techniques that require multiple purification steps and a large amount of organic solvents. We recently identified tomato leaves as an alternative source of solanesol and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479160/ https://www.ncbi.nlm.nih.gov/pubmed/31049434 http://dx.doi.org/10.1016/j.heliyon.2019.e01523 |
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author | Arab, Marjan Bahramian, Bahareh Schindeler, Aaron Fathi, Ali Valtchev, Peter McConchie, Robyn Dehghani, Fariba |
author_facet | Arab, Marjan Bahramian, Bahareh Schindeler, Aaron Fathi, Ali Valtchev, Peter McConchie, Robyn Dehghani, Fariba |
author_sort | Arab, Marjan |
collection | PubMed |
description | Solanesol, the precursor for the synthesis of coenzyme Q10, is currently recovered from tobacco leaves by conventional extraction techniques that require multiple purification steps and a large amount of organic solvents. We recently identified tomato leaves as an alternative source of solanesol and hypothesized that a high-pressure CO(2) extraction could be used as a clean extraction process. The effect of CO(2) pressure and temperature on the extraction of solanesol was determined to achieve high yield and purity. It was found that solanesol could be extracted efficiently by subcritical CO(2) at 25 °C from tomato leaves. The extract contained 40% solanesol and other active compounds such as vitamin K1. A higher level of purity of 93% was achieved using a secondary purification step. Different conventional methods for solanesol extraction was compared to determine the most efficient technique for production of solanesol from tomato leaf. The highest yield of solanesol was achieved at nearly 1% dry weight with using subcritical CO(2), which was superior to conventional methods. |
format | Online Article Text |
id | pubmed-6479160 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-64791602019-05-02 A benign process for the recovery of solanesol from tomato leaf waste Arab, Marjan Bahramian, Bahareh Schindeler, Aaron Fathi, Ali Valtchev, Peter McConchie, Robyn Dehghani, Fariba Heliyon Article Solanesol, the precursor for the synthesis of coenzyme Q10, is currently recovered from tobacco leaves by conventional extraction techniques that require multiple purification steps and a large amount of organic solvents. We recently identified tomato leaves as an alternative source of solanesol and hypothesized that a high-pressure CO(2) extraction could be used as a clean extraction process. The effect of CO(2) pressure and temperature on the extraction of solanesol was determined to achieve high yield and purity. It was found that solanesol could be extracted efficiently by subcritical CO(2) at 25 °C from tomato leaves. The extract contained 40% solanesol and other active compounds such as vitamin K1. A higher level of purity of 93% was achieved using a secondary purification step. Different conventional methods for solanesol extraction was compared to determine the most efficient technique for production of solanesol from tomato leaf. The highest yield of solanesol was achieved at nearly 1% dry weight with using subcritical CO(2), which was superior to conventional methods. Elsevier 2019-04-20 /pmc/articles/PMC6479160/ /pubmed/31049434 http://dx.doi.org/10.1016/j.heliyon.2019.e01523 Text en © 2019 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Arab, Marjan Bahramian, Bahareh Schindeler, Aaron Fathi, Ali Valtchev, Peter McConchie, Robyn Dehghani, Fariba A benign process for the recovery of solanesol from tomato leaf waste |
title | A benign process for the recovery of solanesol from tomato leaf waste |
title_full | A benign process for the recovery of solanesol from tomato leaf waste |
title_fullStr | A benign process for the recovery of solanesol from tomato leaf waste |
title_full_unstemmed | A benign process for the recovery of solanesol from tomato leaf waste |
title_short | A benign process for the recovery of solanesol from tomato leaf waste |
title_sort | benign process for the recovery of solanesol from tomato leaf waste |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479160/ https://www.ncbi.nlm.nih.gov/pubmed/31049434 http://dx.doi.org/10.1016/j.heliyon.2019.e01523 |
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