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A benign process for the recovery of solanesol from tomato leaf waste

Solanesol, the precursor for the synthesis of coenzyme Q10, is currently recovered from tobacco leaves by conventional extraction techniques that require multiple purification steps and a large amount of organic solvents. We recently identified tomato leaves as an alternative source of solanesol and...

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Autores principales: Arab, Marjan, Bahramian, Bahareh, Schindeler, Aaron, Fathi, Ali, Valtchev, Peter, McConchie, Robyn, Dehghani, Fariba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479160/
https://www.ncbi.nlm.nih.gov/pubmed/31049434
http://dx.doi.org/10.1016/j.heliyon.2019.e01523
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author Arab, Marjan
Bahramian, Bahareh
Schindeler, Aaron
Fathi, Ali
Valtchev, Peter
McConchie, Robyn
Dehghani, Fariba
author_facet Arab, Marjan
Bahramian, Bahareh
Schindeler, Aaron
Fathi, Ali
Valtchev, Peter
McConchie, Robyn
Dehghani, Fariba
author_sort Arab, Marjan
collection PubMed
description Solanesol, the precursor for the synthesis of coenzyme Q10, is currently recovered from tobacco leaves by conventional extraction techniques that require multiple purification steps and a large amount of organic solvents. We recently identified tomato leaves as an alternative source of solanesol and hypothesized that a high-pressure CO(2) extraction could be used as a clean extraction process. The effect of CO(2) pressure and temperature on the extraction of solanesol was determined to achieve high yield and purity. It was found that solanesol could be extracted efficiently by subcritical CO(2) at 25 °C from tomato leaves. The extract contained 40% solanesol and other active compounds such as vitamin K1. A higher level of purity of 93% was achieved using a secondary purification step. Different conventional methods for solanesol extraction was compared to determine the most efficient technique for production of solanesol from tomato leaf. The highest yield of solanesol was achieved at nearly 1% dry weight with using subcritical CO(2), which was superior to conventional methods.
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spelling pubmed-64791602019-05-02 A benign process for the recovery of solanesol from tomato leaf waste Arab, Marjan Bahramian, Bahareh Schindeler, Aaron Fathi, Ali Valtchev, Peter McConchie, Robyn Dehghani, Fariba Heliyon Article Solanesol, the precursor for the synthesis of coenzyme Q10, is currently recovered from tobacco leaves by conventional extraction techniques that require multiple purification steps and a large amount of organic solvents. We recently identified tomato leaves as an alternative source of solanesol and hypothesized that a high-pressure CO(2) extraction could be used as a clean extraction process. The effect of CO(2) pressure and temperature on the extraction of solanesol was determined to achieve high yield and purity. It was found that solanesol could be extracted efficiently by subcritical CO(2) at 25 °C from tomato leaves. The extract contained 40% solanesol and other active compounds such as vitamin K1. A higher level of purity of 93% was achieved using a secondary purification step. Different conventional methods for solanesol extraction was compared to determine the most efficient technique for production of solanesol from tomato leaf. The highest yield of solanesol was achieved at nearly 1% dry weight with using subcritical CO(2), which was superior to conventional methods. Elsevier 2019-04-20 /pmc/articles/PMC6479160/ /pubmed/31049434 http://dx.doi.org/10.1016/j.heliyon.2019.e01523 Text en © 2019 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Arab, Marjan
Bahramian, Bahareh
Schindeler, Aaron
Fathi, Ali
Valtchev, Peter
McConchie, Robyn
Dehghani, Fariba
A benign process for the recovery of solanesol from tomato leaf waste
title A benign process for the recovery of solanesol from tomato leaf waste
title_full A benign process for the recovery of solanesol from tomato leaf waste
title_fullStr A benign process for the recovery of solanesol from tomato leaf waste
title_full_unstemmed A benign process for the recovery of solanesol from tomato leaf waste
title_short A benign process for the recovery of solanesol from tomato leaf waste
title_sort benign process for the recovery of solanesol from tomato leaf waste
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479160/
https://www.ncbi.nlm.nih.gov/pubmed/31049434
http://dx.doi.org/10.1016/j.heliyon.2019.e01523
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