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Mast cell degranulation impairs pneumococcus clearance in mice via IL-6 dependent and TNF-α independent mechanisms

BACKGROUND: Mast cells participate in immune responses by releasing potent immune system modifiers via degranulation. Due to currently reported controversial roles of mast cells in Streptococcus pneumoniae infections, this study aimed to determine the role and mechanism of mast cells in clearing S. ...

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Detalles Bibliográficos
Autores principales:	Yang, Jing, Wang, Jichao, Zhang, Xuemei, Qiu, Yulan, Yan, Jurong, Sun, Si, He, Yujuan, Yin, Yibing, Xu, Wenchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	World Allergy Organization 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479162/ https://www.ncbi.nlm.nih.gov/pubmed/31044024 http://dx.doi.org/10.1016/j.waojou.2019.100028

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