Pharmacokinetics of HLD200, a Delayed-Release and Extended-Release Methylphenidate: Evaluation of Dose Proportionality, Food Effect, Multiple-Dose Modeling, and Comparative Bioavailability with Immediate-Release Methylphenidate in Healthy Adults

Objectives: HLD200, an oral, once-daily, evening-dosed, delayed-release, and extended-release methylphenidate (DR/ER-MPH), was designed to provide efficacy from the early morning, throughout the day, and into the evening to individuals with attention-deficit/hyperactivity disorder. The objectives we...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Gobburu, Jogarao V.S., Po, Michelle D., McLean, Angus, DeSousa, Norberto J., Sallee, Floyd R., Incledon, Bev
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6479242/
https://www.ncbi.nlm.nih.gov/pubmed/30810347
http://dx.doi.org/10.1089/cap.2018.0122

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